S100A9 qPCR Primer Pairs, Mouse 基本信息
Target Details
Product Details
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
S100A9 qPCR Primer Pairs, Mouse Alternative Names
60B8Ag qPCR Primer Pairs, Mouse;AW546964 qPCR Primer Pairs, Mouse;BEE22 qPCR Primer Pairs, Mouse;Cagb qPCR Primer Pairs, Mouse;GAGB qPCR Primer Pairs, Mouse;L1Ag qPCR Primer Pairs, Mouse;MRP14 qPCR Primer Pairs, Mouse;p14 qPCR Primer Pairs, Mouse
S100A9 Background Information
S1 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S1 proteins, and the name is derived from the fact that the protein is 1% soluble in ammonium sulfate at neutral pH. Most S1 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S1-A9, also known as S1 calcium-binding protein A9, S1A9, and CAGB, is a member of the S-1 family. S1A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S1A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S1A9 is inhibited by zinc ions. S1A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S1A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
Full Name
S100 calcium binding protein A9
References
Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23. Fanò G. et al., 1995, Prog Neurobiol. 46 (1): 71-82. Vogl T. et al., 2004, Blood. 104: 4260-8. Viemann D. et al., 2005, Blood. 105: 2955-62. Nakatani Y. et al., 2005, Mediators Inflamm. 2005: 280-92. Bjoerk P. et al., 2009, PLoS Biol. 7: E97-E97.