S100A11 qPCR Primer Pairs, Mouse 基本信息
Target Details
Product Details
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
S100A11 qPCR Primer Pairs, Mouse Alternative Names
cal qPCR Primer Pairs, Mouse;Emap1 qPCR Primer Pairs, Mouse;EMAPI qPCR Primer Pairs, Mouse;S100A11 qPCR Primer Pairs, Mouse;S100a14 qPCR Primer Pairs, Mouse;S100c qPCR Primer Pairs, Mouse
S100A11 Background Information
Protein S1-A11, also known as S1 calcium-binding protein A11, S1A11 and MLN7, is a member of the S-1 family. S1A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S1A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S1A11 would trigger conformational changes which would expose the hydrophobic cleft of S1A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S1A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferation of the cancer cells. In the nucleus, S1A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S1A11 is also a novel diagnostic marker in breast carcinoma.
Full Name
S100 calcium binding protein A11
References
Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23. Ohuchida K. et al., 2006, Clin Cancer Res 12 (18): 5417-22. Kouno T. et al., 2008, J Pept Sci. 14 (10): 1129-38. He H. et al., 2009, Cell Biochem Biophys 55 (3): 117-26. Liu XG. et al., 2010, Oncol Rep. 23 (5): 1301-8.
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