产品名称 | Cytochrome P450 4F11 Antibody |
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产品描述 | Rabbit Polyclonal Antibody for Cytochrome P450 4F11 (CYP4F11) detection. Tested with WB in Human. |
文献引用格式 | Cytochrome P450 4F11 Antibody (Boster Biological Technology, Wuhan, China. Catalog #A09078) |
应用范围 | WB |
抗体来源 | Rabbit |
免疫原 | Synthesized peptide derived from internal of human Cytochrome P450 4F11. |
克隆 | Polyclonal |
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产品形态 | Liquid |
内容 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *可以提供无载体抗体。 |
储存条件 | Store at -20℃ for one year, at 4℃ for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20℃ upon receiving. Avoid repeated freezing and thawing. |
基因名 | CYP4F11 |
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基因全名 | Phylloquinone omega-hydroxylase CYP4F11 |
蛋白功能 | Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545). . |
Tissue Specificity | Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. . |
Uniprot ID | CYP4F11 : Q9HBI6 |
为了提供最优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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WB | 1:500-1:3000 |
*最优稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
Western blot analysis of extracts from HeLa cells, using Cytochrome P450 4F11 antibody A09078.
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