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Assay Length
3.25 hours
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Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL)
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Sensitivity
12.5 pg/mL
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Assay Range
156.0 - 5,000 pg/mL (Cell Culture Supernates)12.5 - 500 pg/mL (Cell Culture Supernates),
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Specificity
Human IFN-alpha
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Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
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Interference
No significant interference observed with available related molecules.
Preparation and Storage
Background: IFN-alpha
Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
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Long Name
Interferon alpha
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Entrez Gene IDs
3440 (Human);
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Alternate Names
IFNalpha; IFN-alpha;
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