Preparation and Storage
Background: Fc gamma RIIIB/CD16b
Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.
-
Long Name:
Fc gamma Receptor III
-
Entrez Gene IDs:
2215 (Human); 14131 (Mouse)
-
Alternate Names:
CD16; CD16b antigen; CD16b; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc fragment of IgG, low affinity IIIb, receptor for (CD16); Fc gamma RIIIB; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; Fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcgRIIIB; FcR-10; fcRIII; FCRIIIB; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B