Preparation and Storage
Background: Melanocortin-1 R/MC1R
Melanocortin-1 R/MC1R, the receptor for melanocyte-stimulating hormone (MSH), is a seven pass transmembrane G protein-coupled receptor that controls melanogenesis. Binding of MSH to MC1R activates the receptor and stimulates eumelanin synthesis. MC1R is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.
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Long Name:
Melanocortin 1 Receptor
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Entrez Gene IDs:
4157 (Human); 17199 (Mouse)
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Alternate Names:
CMM5; MC1R; MC1-R; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); Melanocortin receptor 1; Melanocortin-1 R; Melanocortin1R; Melanocortin-1R; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; MSH-RMGC14337; SHEP2; Tob