Preparation and Storage
Background: IL-10 R alpha
Interleukin-10 Receptor alpha (IL-10 R?), also known as IL-10 R1, is a transmembrane ligand-specific component of the IL-10 receptor complex. It associates with IL-10 R beta to mediate the effects of IL-10 in the control of microbial infections, allergic and autoimmune inflammation, and cancer. IL-10 R beta also associates with IL-20 R alpha, IL-22 R alpha, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29. Immunosuppressive signal transduction through the IL-10 receptor complex can be inhibited by activation of TLR2, 4, or 9, enabling strengthened immune responses during infection.
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Long Name:
Interleukin 10 Receptor alpha
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Entrez Gene IDs:
3587 (Human); 16154 (Mouse)
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Alternate Names:
CD210 antigen; CDw210a; HIL-10R; IBD28; IL-10 R alpha; IL-10 receptor subunit alpha; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA; IL-10Ra; IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1; interleukin-10 receptor subunit alpha