Preparation and Storage
Background: IFN-gamma R2
The high-affinity IFN-gamma receptor complex is made up of two type I membrane proteins, IFN-gamma R1 and IFN-gamma R2. Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for signaling but does not bind IFN-gamma by itself.
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Long Name:
Interferon gamma Receptor 2
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Entrez Gene IDs:
3460 (Human); 15980 (Mouse)
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Alternate Names:
AF-1; AF-1interferon-gamma receptor beta chain precursor10IFNGT1Interferon gamma receptor accessory factor 1; IFGR2; IFN-gamma R2; IFN-gamma receptor 2; IFNgammaR2; IFN-gamma-R2; IFNGR2; IFN-gR2; IFNGT1; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor 2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma transducer 1
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