Preparation and Storage
Background: PAFR
PAFR is a seven-transmembrane G protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF binding to PAFR stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system.
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Long Name:
Platelet-activating Factor Receptor
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Entrez Gene IDs:
5724 (Human); 19204 (Mouse); 58949 (Rat)
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Alternate Names:
PAFR; PAF-R; platelet-activating factor receptor; PTAFR
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