Preparation and Storage
Background: Prokineticin R1/PROKR1
Prokineticin Receptor 1 (PKR1), also called ZAQ or GPR73a (G-protein coupled receptor 73a), is a 7-transmembrane glycoprotein of the GPCR family. The extracellular portions of human PKR1 share 81% and 78% aa identity with corresponding portions of mouse PKR1 and human PKR2, with non-identity mainly in the N-terminal sequences. Both PKR1 and PKR2 mediate the effects of prokineticins 1 and 2. This includes mitogenic regulation of angiogenesis in endocrine glands and stimulation of contraction in gastrointestinal smooth muscle.
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Long Name:
Prokineticin Receptor 1
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Entrez Gene IDs:
10887 (Human); 58182 (Mouse); 192648 (Rat)
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Alternate Names:
G protein-coupled receptor 73; G protein-coupled receptor ZAQ; GPR73; GPR73a; GPR73aG-protein coupled receptor 73; PKR1; PK-R1; PKR1G-protein coupled receptor ZAQ; Prokineticin R1; prokineticin receptor 1; ProkineticinR1; PROKR1; ZAQ