Preparation and Storage
Background: OXGR1/GPR80/P2Y15
OXGR1/GPR80 is a receptor for alpha-ketoglutarate that seems to act exclusively through a G(q)-mediated pathway. OXGR1/GPR80 is detected in kidney and, to a lower extent, in placenta. OXGR1/GPR80 mRNA levels were inversely correlated with DNA methylation as examined in paired adjacent normal and tumor samples. Hypermethylated OXGR1/GPR80 is frequent in hepatocellular carcinoma and may be a useful marker in clinical applications.
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Long Name:
Oxoglutarate Receptor 1
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Entrez Gene IDs:
27199 (Human); 239283 (Mouse); 290493 (Rat)
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Alternate Names:
Alpha-ketoglutarate receptor 1; G protein-coupled receptor 80; G protein-coupled receptor 99; GPR80; GPR802-oxoglutarate receptor 1; GPR99; G-protein coupled receptor 80; G-protein coupled receptor 99; MGC119206; MGC119207; MGC119208; OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1; Oxoglutarate Receptor 1; P2RY15; P2RY15P2Y-like GPCR; P2Y purinoceptor 15; P2Y15; P2Y15P2Y-like nucleotide receptor; seven transmembrane helix receptor
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