Preparation and Storage
Background: GPR74/NPFFR2
GPR74, also known as NPFFR2 (neuropeptide FF receptor 2) is a seven-transmembrane glycoprotein of the rhodopsin receptor superfamily. It is activated by neuropeptides such as the morphine-modulating peptides NPAF (A-18-F-amide) and NPFF (F-8-F-amide). Through GPR74 signaling, these neuropeptides also inhibit catecholamine-induced adipocyte lipolysis. GPR74 expression is increased in obese adipose tissue.
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Long Name:
G Protein-coupled Receptor 74
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Entrez Gene IDs:
10886 (Human); 78964 (Rat)
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Alternate Names:
GPR74; GPR74G protein-coupled receptor 74; G-protein coupled receptor 74; neuropeptide FF 2; neuropeptide FF receptor 2; Neuropeptide G-protein coupled receptor; NPFF2; NPFF2G-protein coupled receptor HLWAR77; NPFFR2; NPGPR; NPGPRHLWAR77
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