Preparation and Storage
Background: STAMP2/STEAP4
Human STAMP2, also called Steap4 or TIARP (TNF-alpha-induced adipose-related protein), is a 55 kDa, 459 aa, 6-transmembrane (TM) member of the Steap family of metalloreductases. It is induced by androgens in androgen-regulated prostate cells, and is up-regulated during adipocyte differentiation by TNF-alpha. Full-length human and mouse STAMP2 share 80% aa identity. A 283 aa variant lacks a portion of the oxidoreductase domain and three TM domains. STAMP2 is present in the Golgi complex and early endosomes in addition to the cell surface.
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Long Name:
Six Transmembrane Protein of Prostate 2
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Entrez Gene IDs:
79689 (Human); 117167 (Mouse)
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Alternate Names:
EC 1.16.1; EC 1.16.1.-; FLJ23153; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STAMP2DKFZp666D049; STEAP family member 4; STEAP4; TIARP; TIARPsix transmembrane prostate protein 2; TNFAIP9; Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4; tumor necrosis-alpha-induced adipose-related protein