Preparation and Storage
Background: P2Y12/P2RY12
P2RY12 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY12 is highly expressed in platelets. It is expressed at lower levels in brain. P2RY12 is involved in platelet aggregation. It is a potential target for the treatment of thromboembolisms and other clotting disorders.
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Long Name:
P2Y Purinergic Receptor 12
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Entrez Gene IDs:
64805 (Human); 70839 (Mouse); 64803 (Rat)
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Alternate Names:
ADPG-R; Gi-coupled ADP receptor HORK3; HORK3; HORK3P2Y12 platelet ADP receptor; P2RY12; P2T(AC); P2Y purinoceptor 12; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; P2Y12ADP-glucose receptor; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled, 12; putative G-protein coupled receptor; SP1999; SP1999G-protein coupled receptor SP1999