Preparation and Storage
Background: 2B4/CD244/SLAMF4
2B4, also known as CD244, is a cell surface glycoprotein belonging to the CD2 subgroup of the immunoglobulin superfamily. It acts as a high-affinity receptor for CD48. It is expressed by natural killer (NK) cells and CD8+ T cell subsets. It can regulate killing by CD8+ T cells and NK cells, and IFN-gamma secretion by NK cells. It may also regulate NK cell and T cell proliferation.
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Entrez Gene IDs:
389816 (Human); 51744 (Human); 18106 (Mouse); 227618 (Mouse); 311803 (Rat); 685808 (Rat); 102132700 (Cynomolgus Monkey)
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Alternate Names:
2B4; CD244 antigen; CD244 molecule, natural killer cell receptor 2B4; CD244; h2B4; NAIL; NAILNK cell activation-inducing ligand; natural killer cell receptor 2B4; NKR2B4; NKR2B4NK cell type I receptor protein 2B4,2B4CD244 natural killer cell receptor 2B4; Nmrk; SLAMF4; SLAMF4NK cell activation inducing ligand NAIL
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