Preparation and Storage
Background: DCIR/CLEC4A
DCIR, also known as lectin-like immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. DCIR is expressed on dendritic cells, B cells, monocytes/macrophages and granulocytes.
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Long Name:
Dendritic Cell Immunoreceptor
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Entrez Gene IDs:
50856 (Human); 26888 (Mouse)
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Alternate Names:
CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIR; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR