Preparation and Storage
Background: FoxP3
Human FOXP3 is a 47 kDa member of the P subclass of the forkhead box family of transcription factors. It contains a Leu-rich repeat, a C2H2 zinc finger region, and a C-terminal FKH (forkhead) DNA-binding domain. In human, FOXP3 is found in CD4+, CD8+ and CD4+CD25+ T cells and directly associates with NFAT and NFkB, suppressing their activity in CD4+ T cells.
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Long Name:
Forkhead Box P3
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Entrez Gene IDs:
50943 (Human); 20371 (Mouse)
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Alternate Names:
AIID; AIIDMGC141961; DIETER; forkhead box P3; Forkhead Box Protein P3; FoxP3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; IPEX; JM2; MGC141961; MGC141963; PIDX; PIDXMGC141963; SCURFIN; XPID; XPIDpolyendocrinopathy, enteropathy, X-linked
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