Preparation and Storage
Background: BAMBI/NMA
BAMBI is a type I transmembrane protein that functions as a negative regulator of TGF-beta signaling. The extracellular domain of BAMBI/NMA shares sequence homology with that of TGF-beta RI. BAMBI/NMA lacks an intracellular serine/threonine kinase domain.
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Long Name:
BMP and Activin Membrane-bound Inhibitor
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Entrez Gene IDs:
25805 (Human); 68010 (Mouse)
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Alternate Names:
BAMBI; BMP and activin membrane-bound inhibitor homolog (Xenopus laevis); BMP and activin membrane-bound inhibitor homolog; NMA; NMANon-metastatic gene A protein; Putative transmembrane protein NMA