CEACAM-7 (carcinoembryonic antigen cell adhesion molecule 7; also CGM2) is a 40 - 45 kDa member of the CEACAM subfamily of the CEA family of proteins. It has a restricted expression pattern, being found on epithelium of the colon, appendix and pancreatic ducts. CEACAM-7 is markedly down-regulated in colon carcinoma. Mature human CEACAM-7 is a 209 amino acid (aa), GPI-linked glycoprotein. It contains one V-type (aa 36 - 142) and one C2-type (aa 146 - 233) Ig-like domain, plus a 21 aa C-terminal propeptide. One alternate splice form of CEACAM-7 exists that shows a deletion of aa 143 - 235. No definitive rodent CEACAM-7 has been reported.