Preparation and Storage
Background: CD83
CD83 is member of the Siglec family of transmembrane proteins. CD83 is a type I transmembrane glycoprotein that is a primary marker for dendritic cells. It also exists in multiple forms: membrane-bound CD83 is immunostimulatory while soluble CD83 is immunosuppressive. In the extracellular region, mouse and human CD83 are 66% identical at the aa level.
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Entrez Gene IDs:
9308 (Human); 12522 (Mouse)
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Alternate Names:
B-cell activation protein; BL11; BL11CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; CD83; Cell surface protein HB15; cell-surface glycoprotein; HB15; HB15hCD83