Preparation and Storage
Background: ChemR23
ChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.
-
Long Name:
Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23
-
Entrez Gene IDs:
1240 (Human); 14747 (Mouse); 60669 (Rat)
-
Alternate Names:
CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; ChemR23; cmklr1; Dez; Gpcr27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; MGC126105; MGC126106; orphan G-protein coupled receptor, Dez