Preparation and Storage
Background: SLC7A5/LAT1
SLC7A7 is the light subunit of a cationic amino acid transporter that dimerizes with the heavy subunit transporter protein SLC3A2 (CD98). It is expressed on epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in SLC7A7 are a cause of lysinuric protein intolerance.
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Long Name:
Solute Carrier Family 7 Member 5
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Entrez Gene IDs:
8140 (Human); 20539 (Mouse); 50719 (Rat)
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Alternate Names:
4F2 LC; 4F2LC; CD98; CD98lc; D16S469EL-type amino acid transporter 1; E16; Integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT1hLAT1; MPE16; MPE16CD98 light chain; SLC7A5; sodium-independent neutral amino acid transporter LAT1,4F2LC; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain; Solute carrier family 7 member 5; TA1; y+ system cationic amino acid transporter
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