Preparation and Storage
Background: GLP-1R
GLP-1 R (Glucagon-like Peptide 1 Receptor) is a class B, G protein-linked, seven transmembrane domain protein that is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It is a receptor for Glucagon-like Peptide, a regulator of insulin secretion by pancreatic beta cells. Drugs that target GLP-1 R are of great interest for diabetes related research. Known agonists for GLP-1 R include GLP-1, Boc5, and Cpd1. Following experiments in mouse models, GLP-1 R agonists may also useful in the treatment of acute myocardial infarction.
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Long Name:
Glucagon-like Peptide 1 Receptor
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Entrez Gene IDs:
2740 (Human); 14652 (Mouse)
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Alternate Names:
GLP-1 receptor; GLP1R; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; MGC138331