Preparation and Storage
Background: FPR1
FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N-formyl-methionyl peptides draws neutrophils to sites of infection and promotes degranulation. Human and mouse FPR1 share 73% amino acid sequence identity.
-
Long Name:
Formyl Peptide Receptor 1
-
Entrez Gene IDs:
2357 (Human); 14293 (Mouse); 292409 (Rat)
-
Alternate Names:
fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPR1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor