Preparation and Storage
Background: CD19
CD19 is a 95 kDa transmembrane glycoprotein with two Ig-like C2-set domains. CD19 regulates B cell development and activation through interactions with CD21, CD22, and the B cell receptor. CD19 polymorphisms and upregulation lead to the development of autoimmunity by promoting autoantibody production. Its downregulation is associated with the malignant phenotype in multiple myeloma.
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Entrez Gene IDs:
930 (Human); 12478 (Mouse); 365367 (Rat); 607898 (Canine); 100147468 (Equine)
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Alternate Names:
B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CD19 antigen; CD19 molecule; CD19; CVID3; Differentiation antigen CD19; Leu-12; MGC12802; T-cell surface antigen Leu-12
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