描述
The FluoZin™-1 and FluoZin™-2 indicators are designed to detect Zn
2+ concentrations that are present in synaptic vesicles and released in response to electrical stimulation or excitotoxic agonists. Based on the N-(2-methoxyphenyl)iminodiacetate chelator, these indicators are designed for detection of Zn
2+ in the 0-100 µM range with minimal interfering Ca
2+ sensitivity. FluoZin™ indicators are offered in cell-permeant and cell-impermeant forms.
Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): FluoZin™-1 (~495/515 nm)
• Kd (Zn2+) (in buffer): ~8 µM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cells using microinjection or diffusion from patch pipette Find Fluorescent Indicators for Zinc and Other Metal Ions We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review
Fluorescent Indicators for Zn2+ and Other Metal Ions-Section 19.7 in the Molecular Probes® Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.