描述

The FluoZin™-3 indicator is a Zn ²⁺-selective indicator with a structure that resembles fluo-4. FluoZin™-3 exhibits high Zn ²⁺-binding affinity that is unperturbed by Ca ²⁺ concentrations up to at least 1 µM. In addition, FluoZin™-3 exhibits a >50-fold increase in fluorescence in response to saturating levels of Zn ²⁺. Although imaging applications of FluoZin™-3 are predominant, cell-based microplate assays and flow cytometry protocols have also been developed. FluoZin™-3 indicator is available in a cell-permeant and a cell-impermeant form.

Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): FluoZin™-3 (~494/516 nm)
• K_d (Zn²⁺) (in buffer): ~15 nM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cellsusing microinjection or diffusion from patch pipette

Find Fluorescent Indicators for Zinc and Other Metal Ions
We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn²⁺ and Other Metal Ions—Section 19.7 in the Molecular Probes® Handbook for more information on these products.

For Research Use Only. Not for human or animal therapeutic or diagnostic use.

规格

Indicator Type:	Zinc Indicator
Indicator Properties:	Fluorescent Dye-Based
For Use With (Equipment):	Fluorescence Microscope
Cell Permeability:	Cell-Impermeant
Detection Method:	Fluorescent
Product Line:	FluoZin™
Product Size:	500 µg
Shipping Condition:	Room Temperature

内容及储存