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| Background: | This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | TUBB3 |
| Immunogen: | Fusion protein of human TUBB3 |
| Full name: | tubulin beta 3 class III |
| Synonyms: | CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A |
| SwissProt: | Q13509 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human cervical cancer and Human tonsil |
| IHC Recommend dilution: | 30-150 |
| WB Predicted band size: | 50 kDa |
| WB Positive control: | Hela, A549 and PC-3 cell lysates |
| WB Recommended dilution: | 1000-5000 |
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