Features and Benefits

? Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects.
? Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets.
? Library contains all human mature miRNAs in miRBase version 21.
? Coverage includes 2,754 miRNA mimics
? Optimized and ready for transfection.
? Library is in 96-well format, and 384-well plate format is available upon request.
? Negative controls included in each plate of the miRNA mimic library. 
? Available as a whole human library and individual miRNA targets.
? Email us acctreps-hou@sial.com for more information.

General description

The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute).

法律信息

MISSION is a registered trademark of Sigma-Aldrich Co. LLC