General description

The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute).

? Optimized and ready for transfection.
? Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets.
? Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects.
? Available as a whole human library and individual miRNA targets.

Other Notes

miRBase V18 Mature ID update: hsa-miR-181c-5p

法律信息

MISSION is a registered trademark of Sigma-Aldrich Co. LLC