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Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
PAK1 is a member of the p21-activated kinases (PAKs) which have been implicated in the regulation of gene transcription, cell morphology, motility and apoptosis. PAKs are serine/threonine kinases which bind to and are activated by small GTPases, CDC42 (cell division cycle 42) and RAC. PAK1 belongs to the Group I PAKs which also includes PAK2 and PAK3. PAK1 is a key regulator of the actin cytoskeleton, adhesion and cell motility.
PRECISIO 为以下机构的注册商标: Sigma-Aldrich Co. LLC
recombinant | expressed in baculovirus infected Sf9 cells |
grade | PRECISIO® Kinase |
assay | ≥70% (SDS-PAGE) |
form | buffered aqueous glycerol solution |
activity | 40-53 nmol/min·mg |
mol wt | mol wt ~96 kDa |
shipped in | dry ice |
storage temp. | ?70°C |
Gene Information | human ... PAK1(5058) |
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