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Popular Documents: Datasheet (PDF)
CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.
PRECISIO 为以下机构的注册商标： Sigma-Aldrich Co. LLC
| recombinant | expressed in baculovirus infected Sf9 cells |
| grade | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| activity | 17-22 nmol/min·mg |
| mol wt | CDK7 subunit mol wt ~40 kDa |
| MNAT1 subunit mol wt ~37 kDa | |
| cyclin D1 mol wt ~39 kDa | |
| shipped in | dry ice |
| storage temp. | ?70°C |
| Gene Information | human ... CCNH(902), CDK7(1022), MNAT1(4331) |
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