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BMPR2 (174-end), active, His tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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号:SRP5209-10UG

牌:Sigma 西格玛

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别名: BMPR-II BMPR3 BMR2 BRK-3 FLJ41585 FLJ76945 PPH1 T-ALK

产品名称

General description

BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs that are involved in endochondral bone formation and embryogenesis. The loss of interaction and lack of phosphorylation of TCTEL1 by BMPR2 may contribute to the pathogenesis of primary pulmonary hypertension (PPH) and BMPR2 also plays an essential role in human T-cell differentiation.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Physical form

Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

法律信息

PRECISIO 为以下机构的注册商标: Sigma-Aldrich Co. LLC


性质

recombinant   expressed in baculovirus infected Sf9 cells
grade   PRECISIO® Kinase
assay   ≥70% (SDS-PAGE)
form   buffered aqueous glycerol solution
activity   11.9-16.1 nmol/min·mg
mol wt   mol wt ~115 kDa
NCBI accession no.   NM_001204
shipped in   dry ice
storage temp.   ?70°C
Gene Information   human ... BMPR2(659)

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