Application

Aprotinin is largely used as an inhibitor of trypsin.

包装

1 mg in glass bottle

25, 100 mg in poly bottle

Preparation Note

A further purification of A1153 to yield a product with slightly higher activity and purity

Unit Definition

One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of N-alpha-benzoyl-DL-arginine p-nitroanilide per minute at pH 7.8 and 25°C. Another commonly used unit is the KIU, with 1 TIU = 1,300 KIU.

One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmole of N-α-benzoyl- DL -arginine p-nitroanilide (BAPNA) per min at pH 7.8 at 25 °C.

Biochem/physiol Actions

可以抑制胰蛋白酶、胰凝乳蛋白酶、激肽释放酶以及纤溶酶的丝氨酸蛋白酶抑制剂。