MDL number MFCD01635659
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This protein phosphatase inhibitor 1 is suitable for use as a substrate to identify novel phosphatases and kinases that modulate protein phosphatase inhibitor 1 activity. This product is also suitable for use in affinity pull-down binding studies.
Intimately involved in glycogen metabolism as an inhibitor of phosphorylase phosphatase, the enzyme responsible for conversion of phosphorylase b to phosphorylase a. Inhibition is invoked only upon phosphorylation by a cAMP-dependent protein kinase.
Supplied as a solution in 50 mM Tris-HCl, pH 7.0, containing 0.1 mM PMSF, 14 mM 2-mercaptoethanol, and 10% glycerol
recombinant | expressed in E. coli |
assay | >95% (SDS-PAGE) |
mol wt | apparent mol wt ~27 kDa |
mol wt ~31 kDa | |
shipped in | dry ice |
storage temp. | ?70°C |
Gene Information | human ... PPP1R1A(5502), PPP1R8(5511) |
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