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经验分子式（希尔表示法） C21H25N · HCl
分子量 327.89
MDL number MFCD00145430
Popular Documents: Specification Sheet (PDF)
Mode of Action: Inhibits squalene epoxidase, preventing biosynthesis of ergosterol.
Antimicrobial spectrum: Antifungal and antimycotic. Fungicidal against dermatopytes and some yeasts; fungistatic against Candida albicans.
Terbinafine inhibits squalene monooxygenase thereby blocking the biosynthesis of ergosterol, which is an essential component of fungal cell membranes. The inhibition of squalene monooxygenase also results in the accumulation of squalene. Terbinafine hydrochloride is highly lipophilic and tends to accumulate in skin, nails, and fatty tissues. It is antifungal and antimycotic. It is fungicidal against dermatopytes and some yeasts and is fungistatic against Candida albicans.
Allylamine derivative.
100, 250 mg in poly bottle
Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies.
| assay | ≥98% |
| form | powder |
| solubility | methanol: soluble50 mg/mL |
| Mode of action | enzyme | inhibits |
| antibiotic activity spectrum | fungi |
| yeast |
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