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线性分子式 C20H38N6O4 · 1/2H2SO4
分子量 475.59
MDL number MFCD00037012
PubChem Substance ID 24896328
Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
由于三种形式在溶液中达到平衡，亮抑酶肽可在 HPLC 上形成多个峰。通过三个主峰测定纯度。主要的杂质肽为
5, 10, 25, 50, 100, 250 mg in glass bottle
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
| Quality Level | PREMIUM |
| biological source | microbial |
| assay | ≥90% (HPLC) |
| solubility | H2O: soluble10 mM (Solutions are stable for a week at 4 °C. Stock solutions are stable up to 6 months at ?20 °C.) |
| H2O: soluble50 mg/mL | |
| storage temp. | ?20°C |
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