One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25°C.
Adenosine deaminase (ADA) is a key enzyme in purine metabolism and is essential for normal immune function . It is important in the study of immune system diseases such as rheumatoid arthritis .
Adenosine deaminase irreversibly deaminates adenosine to inosine. In addition to immune system regulation, ADA may be involved in epithelial cell differentiation, neurotransmission and gestation maintenance .
recombinant | expressed in E. coli |
storage temp. | ?20°C |
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