Features and Benefits

Stabilized without non-physiologic mutations

包装

100 unit vial containing ≥ 100ug protein

Preparation Note

Bioengineered to resist autoproteolysis, resulting in an enzyme with improved stability and substantially higher activity levels over extended time periods to conduct kinetic assays. The enzyme includes the most commonly occurring background polymorphism (L63P) that aids in the drug resistance profile.

Unit Definition

One unit of HIV protease will cleave 1picomole per minute of the substrate Abz-Ala-Arg-Val-Nle-Tyr(NO₂)-Glu-Ala-Nle-NH₂ at 37°C.

Physical form

Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol.