Biochem/physiol Actions

Urokinase expression and invasiveness suppression by urinary trypsin inhibitor acts through MEK/ERK/c-Jun-dependent signaling pathways.

Unit Definition

One unit will activate that amount of plasminogen which will produce a ΔA₂₇₅ of 1.0 per ml per minute at pH 7.5 at 37 °C, when measuring perchloric acid soluble products from α-casein (1 cm light path).

Physical form

Lyophilized from 1 mL of 50 mM Tris-HCl, pH 7.4 with 100 mM NaCl, 0.1% PEG 6000, and 200 mM mannitol

Physical properties

High molecular weight form migrating at 54 kDa by SDS-PAGE under non-reducing conditions