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LMPTP-A 250ug

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货号：14-619M

品牌：Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-619
Brand Family Upstate
Trade Name
  • Upstate
Description LMPTP-A Protein, 10 µg
Overview GST-tagged, recombinant, full length, human LMPTP-A
References
Product Information
Applications
Application GST-tagged, recombinant, full length, human LMPTP-A, for use in Phosphatase Assays.
Key Applications
  • Phosphatase Assay
Biological Information
Source Expressed in E. coli
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene Summary The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene.
Gene Symbol
  • ACP1
  • HAAP
  • LMW-PTP
  • LMW-PTPase
  • MGC3499
  • MGC111030
Protein Target LMPTP-A
Purification Method Glutathione agarose affinity chromatography
Target Sub-Family Tyr phosphatase
UniProt Number
UniProt Summary FUNCTION: SwissProt: P24666 # Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
SIZE: 158 amino acids; 18042 Da
SUBUNIT: Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: T-lymphocytes express only isoform 2.
SIMILARITY: SwissProt: P24666 ## Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Molecular Weight 44.5kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by dephosphorylation of DiFMUP
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions 6 months at -70°C
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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