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eEF-2K, active 250ug

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号:14-654M

牌:Millipore 密理博

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Replacement Information
Description
Catalogue Number 14-654
Brand Family Upstate
Trade Name
  • Upstate
Description eEF-2K Protein, active, 10 µg
Overview N-terminal GST-tagged, recombinant, human eEF-2K, amino acids 2-end
References
Product Information
Applications
Application Active, N-terminal GST-tagged, recombinant, human eEF-2K, amino acids 2-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Source expressed in E. coli cells
Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene Summary This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Gene Symbol
  • EEF2K
  • MGC45041
  • HSU93850
  • eEF-2K
Protein Target eEF-2K
Purification Method Glutathione-agarose
Target Sub-Family Misc
UniProt Number
UniProt Summary FUNCTION: SwissProt: O00418 # Phosphorylates eukaryotic elongation factor-2. Binds calmodulin (By similarity).
SIZE: 725 amino acids; 82172 Da
SUBUNIT: Monomer or homodimer (Potential).
SIMILARITY: SwissProt: O00418 ## Contains 1 alpha-type protein kinase domain.
Molecular Weight 108.5kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance routinely evaluated by phosphorylation of EF2tide (Catalog# 12-560)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions stable 6 months at -70°C from date of shipment
Packaging Information
Material Size 10 µg
Transport Information
Supplemental Information
Specifications

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