Anti-GABAA Receptor Beta 1 Subunit Affinity Purified (rabbit polyclonal) - 炼石商城

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Anti-GABAA Receptor Beta 1 Subunit Affinity Purified (rabbit polyclonal)

市场价：: 0.00

促销价：: ¥0.00

货号：AB9680

品牌：Millipore 密理博

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北京朝阳

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB9680
Replaces	AB5451
Brand Family	Chemicon®
Trade Name	Chemicon
Description	Anti-GABA A Receptor β 1 Antibody

References

Product Information
Format	Affinity Purified
Presentation	Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Applications
Application	This Anti-GABA A Receptor β 1 Antibody is validated for use in WB for the detection of GABA A Receptor β 1.
Key Applications	Western Blotting
Application Notes	Western blot: 1:1,000. Optimal working dilutions must be determined by the end user.

Biological Information
Immunogen	Fusion protein from the Cytosolic loop of rat the GABAA Receptor beta 1 subunit.
Host	Rabbit
Specificity	GABAA Receptor beta 1 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor beta 1 subunit in lysates from rat cerebellum and cortex.
Species Reactivity	Human Mouse Rat
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NM_000812.2
Entrez Gene Summary	The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Gene Symbol	GABRB1 GABA
UniProt Number	P18505
UniProt Summary	FUNCTION: SwissProt: P18505 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. SIZE: 474 amino acids; 54235 Da SUBUNIT: Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. SIMILARITY: SwissProt: P18505 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family.

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Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.

Packaging Information
Material Size	100 µL

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