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Anti-hPPARd (rabbit polyclonal)

市场价：: 0.00

促销价：: ¥0.00

货号：AB10094

品牌：Millipore 密理博

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北京朝阳

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB	Rb	Serum	Polyclonal Antibody

Description
Catalogue Number	AB1094
Description	Anti-Myosin X Antibody
Alternate Names	Unconventionnal myosin-X Unconventional myosin-10
Background Information	Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).

References

Product Information
Format	Serum
Control	Human head/neck lysate.
Presentation	Rabbit serum containing 0.05% NaN3.

Applications
Application	Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.
Key Applications	Western Blotting

Biological Information
Immunogen	KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.
Epitope	a.a. 936-953
Host	Rabbit
Specificity	Cat. No. AB1094 recognizes human Myosin X.
Species Reactivity	Human Mouse Rat
Species Reactivity Note	Human. Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.
Antibody Type	Polyclonal Antibody
Entrez Gene Number	AAF37875
Gene Symbol	MYO10
UniProt Number	Q9HD67
UniProt Summary	FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a role in regions of dynamic actin. SUBUNIT STRUCTURE: Interacts with ECM29. CAUTION: Represents a unconventional myosin. This protein should not be confused with the conventional myosin-10 (MYH10). SIZE: 237 kDa
Molecular Weight	~ 108 kDa

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintain at -20°C for up to 1 year from date of receipt. Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

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