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Anti-ABC (ATP binding cassette) family B member 1a (rabbit polyclonal)

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货号：AB10340

品牌：Millipore 密理博

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Replacement Information

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
M, R WB Rb Serum Polyclonal Antibody
Description
Catalogue Number AB10340
Brand Family Chemicon®
Trade Name
  • Chemicon
Description Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A
Alternate Names
  • ATP binding cassette transporter 1
  • ATP-binding cassette 1
  • ATP-binding cassette transporter 1
  • ATP-binding cassette, sub-family A (ABC1), member 1
  • ATP-binding cassette, sub-family A member 1
  • ATP-binding cassette, sub-family A, member 1
  • Cholesterol efflux regulatory protein
Background Information This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.
References
Product Information
Format Serum
Presentation Raw rabbit serum with 0.05% sodium azide.
Applications
Application Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application Notes Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.
Biological Information
Immunogen Recombinant
Epitope AA N629 – W704
Host Rabbit
Species Reactivity
  • Mouse
  • Rat
Species Reactivity Note Mouse. Expected to react with rat based on sequence homology.
Antibody Type Polyclonal Antibody
Entrez Gene Number
Entrez Gene Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq]
Gene Symbol
  • ABC-1
  • ABC1
  • CERP
  • FLJ14958
  • HDLDT1
  • MGC164864
  • MGC165011
  • OTTHUMP00000021833
  • TGD
  • membrane-bound
Molecular Weight 141 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Maintain at -20°C for up to 12 months from date of receipt.
Packaging Information
Material Size 50 µL
Transport Information
Supplemental Information
Specifications

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