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Anti-Bcl-6 (C-term)

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货号：04-437

品牌：Millipore 密理博

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Replacement Information

特卖

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重要规格表

Species Reactivity Key Applications Host Format Antibody Type
R WB Rb Affinity Purified Polyclonal Antibody
Description
Catalogue Number ABC1480
Replaces 04-437
Description Anti-BCL6 Antibody
Alternate Names
  • B-cell lymphoma 6 protein
  • BCL-6
  • B-cell lymphoma 5 protein
  • BCL-5
  • Protein LAZ-3
  • Zinc finger and BTB domain-containing protein 27
  • Zinc finger protein 51
  • BCL6
Background Information BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
References
Product Information
Format Affinity Purified
Presentation Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Applications
Application This Anti-BCL6 Antibody is validated for use in Western Blotting for the detection of BCL6.
Key Applications
  • Western Blotting
Biological Information
Immunogen BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.
Epitope Near Center
Concentration Please refer to lot specific datasheet.
Host Rabbit
Species Reactivity
  • Rat
Antibody Type Polyclonal Antibody
Gene Symbol
  • BCL6
  • BCL5
  • LAZ3
  • ZBTB27
  • ZNF51
Purification Method Antigen Affinity Purified
UniProt Number
Molecular Weight ~68 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance Evaluated by Western Blotting/Peptide Inhibition Assay in rat lung tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected BCL6 in 15 µg of rat lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size 100 μg
Transport Information
Supplemental Information
Specifications

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