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Mertansine (DM1)是一种微管蛋白抑制剂，它在微管的末端结合并抑制微管的动态性。 Mertansine是一种抗体可缀合的美登木素生物碱，用于克服与美登素相关的全身毒性并增强肿瘤特异性递送。
| Description | Mertansine (DM1) is a microtubulin inhibitor which binds at the tips of microtubules and suppresses the dynamicity of microtubules.. Mertansine is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. | ||||||||||||||||
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| Solvent & Solubility | In Vitro: DMSO : ≥ 83.33 mg/mL (112.87 mM) * "≥" means soluble, but saturation unknown. Preparing Stock Solutions
* Please refer to the solubility information to select the appropriate solvent. | ||||||||||||||||
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